“Mass vaccination with an improperly tested vaccine is unethical,” he said. “Any problem with the Russian vaccination campaign would be disastrous both through its negative effects on health, but also because it would further set back the acceptance of vaccines in the population.”Scientific papersHis comments were echoed by Danny Altmann, a professor of Immunology at Imperial College London, who said the “collateral damage” from deploying any vaccine that is not yet known to be safe and effective “would exacerbate our current problems insurmountably”.Even as Russia declared victory, more than half a dozen drugmakers around the world are in the process of conducting large-scale, advanced human trials of their potential COVID-19 vaccines, each with tens of thousands of volunteer participants.Several of these frontrunners, including Moderna, Pfizer and AstraZeneca, say they hope to know if their vaccines work and are safe by the end of this year.All are expected to publish their trial results and safety data and submit them to regulators in the United States, Europe and elsewhere for scrutiny before any license could be granted.The Russian vaccine’s approval by the Health Ministry comes before trials that would normally involve thousands of participants, commonly known as a Phase III trial. Such trials are usually considered essential precursors for a vaccine to secure regulatory approval.Peter Kremsner, an expert at Germany’s University Hospital in Tuebingen who is working on clinical trials of a vaccine candidate from CureVac, said Russia’s move was “reckless”.”Normally you need a large number of people to be tested before you approve a vaccine,” he said. “I think it’s reckless to do that if lots of people haven’t already been tested.”Experts said the lack of published data on Russia’s vaccine – including how it is made and details on safety, immune response and whether can prevent COVID-19 infection – leaves scientists, health authorities and the public in the dark.”It is not possible to know if the Russian vaccine has been shown to be effective without submission of scientific papers for analysis,” said Keith Neal, a specialist in the epidemiology of infectious diseases at Britain’s Nottingham University. She said such a super-fast approval could mean that potential adverse effects of a vaccine may not be picked up. These, while likely to be rare, could be serious, she warned.Russian President Vladimir Putin said the vaccine, developed by Moscow’s Gamaleya Institute, was safe and that it had been administered to one of his daughters.”I know that it works quite effectively, forms strong immunity, and I repeat, it has passed all the needed checks,” Putin said on state television.Francois Balloux, an expert at University College London’s Genetics Institute, said it was “a reckless and foolish decision”. Topics : An announcement by Russia on Tuesday that it will approve a COVID-19 vaccine after less than two months of human testing prompted alarm among global health experts, who said that with no full trial data, the vaccine is hard to trust.Intent on being first in the global race to develop a vaccine against the pandemic disease, Russia has yet to conduct large-scale trials of the shot that would produce data to show whether it works – something immunologists and infectious disease experts say could be a “reckless” step.”Russia is essentially conducting a large population level experiment,” said Ayfer Ali, a specialist in drug research at Britain’s Warwick Business School.
RANCHO CUCAMONGA – A judge ruled Tuesday that prosecutors have sufficient evidence to take an inmate to trial on charges he killed a guard at the men’s state prison in Chino. The ruling in the case against Jon Christopher Blaylock follows more than two years of legal delays. Even still, attorneys said afterward they believe it will be at least two more years before the case gets to a jury. “There are still a lot of things to look into,” said Deputy Public Defender Steve Mapes. An investigator on the case, San Bernardino County sheriff’s Detective Rod Medley, testified he interviewed a Sycamore Hall inmate who saw Blaylock stab Gonzalez. The detective said the inmate saw Blaylock call Gonzalez toward him. Medley said the witness told him Gonzalez and Blaylock began walking together near a row of cells when Blaylock pulled a knife from his waistband and began stabbing the officer. “He described it as, `Boom, boom, boom,’ really forceful blows,” the detective testified. Coroner’s pathologist Steven Trenkle, who performed the autopsy on Gonzalez, testified the correctional officer suffered three stab wounds to the chest and abdomen and another to the arm. One of the wounds pierced his heart. Two others damaged his pancreas and spleen, Trenkle testified. After hearing the evidence, Judge Ingrid Uhler ruled prosecutors have sufficient evidence to take Blaylock to trial. Blaylock’s attorneys did not argue against the charges during the hearing. However, they said they plan to file motions challenging the counts prior to trial. Blaylock was charged about a month after the stabbing, but his case has moved slowly through the courts. Much of the delay was caused early on, when prosecutors improperly obtained Blaylock’s confidential psychological records. The move prompted extensive hearings that resulted in the judge recusing a large portion of the San Bernardino County District Attorney’s Office from the case. Defense attorneys Mapes and Joseph Canty said Tuesday they still need significant time to prepare for a trial because they have found numerous irregularities and flaws in the investigation into the stabbing. Deputy District Attorney Joanne Uhlman said that because Blaylock faces the death penalty, his lawyers will probably be given as much time as they say they need to get ready. Blaylock is set to return to West Valley Superior Court on March 26 to be arraigned. [email protected] (909) 483-9325 160Want local news?Sign up for the Localist and stay informed Something went wrong. Please try again.subscribeCongratulations! You’re all set! Prosecutors are seeking the death penalty for Blaylock, who is charged with murder and assault by a life prisoner in connection with the Jan. 10, 2005, stabbing of Correctional Officer Manuel Gonzalez. Gonzalez, of Whittier was stabbed four times while on duty at the California Institution for Men state prison. Blaylock, 37, was at the prison serving a life term for attempting to murder a police officer. Investigators say guards had released Blaylock from his cell inside the prison’s Sycamore Hall housing unit in an attempt to quell racial tensions when Gonzalez was attacked. Blaylock appeared in West Valley Superior Court on Tuesday for the second day of testimony in his preliminary hearing.